SCHEMBL10898445

SCHEMBL10898445

COCCN(C(=O)C(C)Cl)c1cc(C)ccc1C

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 6/20 0.42
ATM Q13315 1/20 0.42
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
KMT2A Q03164 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
TAS1R2 Q8TE23 1/20 0.37
KDM4E B2RXH2 3/20 0.35
TSHR P16473 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GLA P06280 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
POLB P06746 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10897850 0.88 ALDH1A1 (0.33) HPGDCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL10896634 0.87 MAPT (0.36) HPGDALDH1A1TP53KDM4ETSHR
SCHEMBL10344995 0.84 TP53 (0.59) HPGDCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL11876798 0.82 MAPT (0.36) HPGDALDH1A1MEN1TP53KMT2A
SCHEMBL10527654 0.76 MEN1 (0.43) HPGDCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL10896448 0.75 KMT2A (0.42) HPGDALDH1A1MEN1TP53KMT2A
SCHEMBL10900094 0.74 TP53 (0.60) HPGDCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL10896138 0.73 TP53 (0.43) HPGDCYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL11876847 0.72 KDM4E (0.35) ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL10895624 0.72 MEN1 (0.45) ALDH1A1MEN1TP53KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4581060-A PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1986-04-08 US disclosed
US-4548756-A PLANT GROWTH REGULATORS, PLANT SAFENING AGENTS CIBA GEIGY CORPORATION (US) 1985-10-22 US disclosed
US-4532732-A PLANT SAFENING AGENTS AND CHLOROACETANILIDE HERBICIDES FOR SERGHUM, RICE AND BARLEY CIBA-GEIGY CORPORATION (US) 1985-08-06 US disclosed
US-4530798-A Containing phenyl or naphthyl ring CIBA-GEIGY CORPORATION (US) 1985-07-23 US disclosed
US-4518536-A Compositions, which promote plant growth and protect plants, based on oxime ethers and oxime esters CIBA-GEIGY CORPORATION (US) 1985-05-21 US disclosed
US-4497745-A Compositions, which promote plant growth and protect plants based on oxide ethers and oxime esters CIBA-GEIGY CORPORATION (US) 1985-02-05 US disclosed
US-4497648-A ANTIDOTES FOR HERBICIDES FOR PLANTS CIBA-GEIGY CORPORATION (US) 1985-02-05 US disclosed
US-4472317-A Compositions which promote plant growth and protect plants, based on oxime ethers and oxime esters CIBA-GEIGY CORPORATION (US) 1984-09-18 US disclosed
US-4466822-A PLANT GROWTH REGULATORS; PLANT SAFENING AGENTS CIBA-GEIGY CORPORATION (US) 1984-08-21 US disclosed
US-4451286-A PLANT SAFENING CIBA-GEIGY CORPORATION (US) 1984-05-29 US disclosed
US-4415743-A PLANT GROWTH REGULATORS; PLANT SAFENING AGENTS; ANTIDOTES CIBA-GEIGY CORPORATION (US) 1983-11-15 US disclosed
US-4227917-A Phenylglyoxylonitrile-2-oxime-cyanomethyl ether as a crop safener CIBA-GEIGY CORPORATION (US) 1980-10-14 US disclosed
US-4225334-A USED WITH HERBICIDES CIBA-GEIGY CORPORATION (US) 1980-09-30 US disclosed
US-4220464-A Phenylglyoxylonitrile-2-oxime-cyanomethyl ether as plant growth regulator CIBA-GEIGY CORPORATION (US) 1980-09-02 US disclosed
US-4152137-A PREEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1979-05-01 US disclosed
US-4070179-A Plant growth regulation with N-(2-alkoxy-ethyl)-N-chloroacetyl-2,3,6-trimethyl-anilines CIBA-GEIGY CORPORATION (US) 1978-01-24 US disclosed