Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345114 | 1.00 | DRD2 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9503689 | 0.90 | DRD2 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9503686 | 0.90 | DRD2 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL8727511 | 0.86 | CYP2C9 (0.43) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9809484 | 0.85 | DRD2 (0.41) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9809489 | 0.85 | DRD2 (0.41) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL10794856 | 0.84 | RARB (0.47) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL10555303 | 0.81 | CYP2C9 (0.50) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL10794463 | 0.79 | CYP2C9 (0.51) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL10794457 | 0.79 | CYP2C9 (0.51) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205998-B1 | CYCLOHEXANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME | Chisso Corporation (JP) | 1990-02-28 | — | — | EP | disclosed |
| US-4797228-A | Cyclohexane derivative and liquid crystal composition containing same | CHISSO CORPORATION (JP) | 1989-01-10 | — | — | US | disclosed |
| EP-0205998-A1 | Cyclohexane derivative and liquid crystal composition containing same | Chisso Corporation (JP) | 1986-12-30 | — | — | EP | disclosed |