SCHEMBL10345141

SCHEMBL10345141

CCC[C@H]1CC[C@H](C=Cc2ccc(-c3ccc(F)c(F)c3)cc2)CC1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.35
MAOB P27338 13/20 0.34
MAOA P21397 3/20 0.34
CYP17A1 P05093 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
KIF11 P52732 1/20 0.31
GRIN2B Q13224 1/20 0.31
NR1H4 Q96RI1 1/20 0.31
NPY5R Q15761 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10345138 0.86 NFE2L2 (0.39) NFE2L2MAOBMAOA
SCHEMBL10345137 0.86 NFE2L2 (0.39) NFE2L2MAOBMAOA
SCHEMBL10345140 0.86 NFE2L2 (0.39) NFE2L2MAOBMAOA
SCHEMBL10345136 0.86 NFE2L2 (0.39) NFE2L2MAOBMAOA
SCHEMBL17083203 0.86 MAOB (0.38) MAOBMAOACYP17A1CYP11B1
SCHEMBL15744237 0.82 MAOB (0.31) MAOBMAOA
SCHEMBL27935712 0.81 MAOB (0.50) MAOBMAOA
SCHEMBL8833894 0.80 RECQL (0.30)
SCHEMBL8833900 0.80 RECQL (0.30)
SCHEMBL8833888 0.80 RECQL (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4917819-A Cyclohexane derivative and liquid crystal composition containing same CHISSO CORPORATION (JP) 1990-04-17 US disclosed
EP-0205998-B1 CYCLOHEXANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME Chisso Corporation (JP) 1990-02-28 EP disclosed
US-4797228-A Cyclohexane derivative and liquid crystal composition containing same CHISSO CORPORATION (JP) 1989-01-10 US disclosed
EP-0205998-A1 Cyclohexane derivative and liquid crystal composition containing same Chisso Corporation (JP) 1986-12-30 EP disclosed