Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345719 | 0.90 | HMGCR (0.50) | HMGCR | |
| SCHEMBL8880612 | 0.86 | HMGCR (0.39) | HMGCRCTSA | |
| SCHEMBL10345400 | 0.85 | CTSA (0.34) | HMGCRCTSA | |
| SCHEMBL8953497 | 0.82 | — | — | |
| SCHEMBL8953516 | 0.82 | — | — | |
| SCHEMBL8953145 | 0.78 | HMGCR (0.49) | HMGCR | |
| SCHEMBL8953146 | 0.78 | HMGCR (0.49) | HMGCR | |
| SCHEMBL8880604 | 0.77 | HMGCR (0.36) | HMGCRCTSA | |
| SCHEMBL10345348 | 0.76 | NR4A2 (0.42) | HMGCR | |
| SCHEMBL10345393 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356788-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1990-03-07 | — | — | EP | claimed |
| EP-0356788-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1990-03-07 | — | — | EP | disclosed |