Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | IDUA | P35475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345486 | 1.00 | HTT (0.41) | HTTARG1ALDH1A1APLNRKMT2A | |
| SCHEMBL16325499 | 0.70 | HTT (0.34) | HTT | |
| SCHEMBL13801439 | 0.69 | HTT (0.33) | HTTALDH1A1 | |
| SCHEMBL3432004 | 0.68 | HTT (0.35) | HTTARG1APLNRKMT2A | |
| SCHEMBL7271734 | 0.67 | HTT (0.38) | HTTAPLNR | |
| SCHEMBL3939441 | 0.67 | HTT (0.38) | HTTAPLNR | |
| SCHEMBL9214332 | 0.67 | HTT (0.38) | HTTALDH1A1KMT2A | |
| SCHEMBL3290650 | 0.67 | HTT (0.34) | HTT | |
| Hydrochloric Acid SCHEMBL10909627 | 0.66 | ALDH1A1 (0.39) | ALDH1A1KMT2A | |
| SCHEMBL10943324 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171159-B1 | SUBSTITUTED AZETIDINONE COMPOUNDS, THEIR PREPARATION, AND MEDICAMENTS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4719207-A | CENTRAL NERVOUS SYSTEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-01-12 | — | — | US | disclosed |
| EP-0171159-A1 | Substituted azetidinone compounds, their preparation, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-02-12 | — | — | EP | disclosed |