Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | CD44 | P16070 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16940688 | 0.90 | LMNA (0.59) | LMNACD44GABRA1GABRB1GAA | |
| SCHEMBL25552477 | 0.87 | LMNA (0.68) | LMNACD44GABRA1GABRB1GAA | |
| SCHEMBL13963581 | 0.87 | LMNA (0.50) | LMNACD44GABRA1GABRB1GAA | |
| SCHEMBL11862411 | 0.87 | LMNA (0.52) | LMNAGABRA1GABRB1TSHRTP53 | |
| SCHEMBL14558056 | 0.85 | LMNA (0.54) | LMNACD44GABRA1GABRB1GAA | |
| SCHEMBL21145864 | 0.85 | LMNA (0.48) | LMNACD44GABRA1GABRB1GAA | |
| SCHEMBL12091749 | 0.85 | LMNA (0.65) | LMNACD44GABRA1GABRB1GAA | |
| SCHEMBL12297358 | 0.85 | LMNA (0.59) | LMNACD44GABRA1GABRB1GAA | |
| SCHEMBL26813445 | 0.82 | LMNA (0.56) | LMNACD44GABRA1GABRB1GAA | |
| SCHEMBL13818324 | 0.81 | LMNA (0.48) | LMNAGABRA1GABRB1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257866-B1 | PROCESS FOR PRODUCING 2,5-DICHLOROTOLUENE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-03-07 | — | — | EP | claimed |
| US-4822928-A | Process for producing 2,5-dichlorotoluene | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-04-18 | — | — | US | claimed |
| EP-0257866-A1 | Process for producing 2,5-dichlorotoluene | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-03-02 | — | — | EP | claimed |
| JP-63039828-A | — | — | None | — | — | JP | disclosed |
| WO-2024103400-A1 | POLYCYCLIC COMPOUND AS GPR75 ACTIVATOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 水木未来(北京)科技有限公司 | 2024-05-23 | — | — | WO | disclosed |
| US-20230234950-A1 | CRBN LIGANDS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-27 | — | — | US | disclosed |
| EP-0257866-B1 | PROCESS FOR PRODUCING 2,5-DICHLOROTOLUENE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4822928-A | Process for producing 2,5-dichlorotoluene | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0257866-A1 | Process for producing 2,5-dichlorotoluene | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-03-02 | — | — | EP | disclosed |
| JP-S6339828-A | PRODUCTION OF 2,5-DICHLOROTOLUENE | KUREHA CHEM IND CO LTD | 1988-02-20 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234950-A1 | CRBN LIGANDS AND USES THEREOF | CRBN, CRKL, ERBB3 | LMNA 2932/4885CD44 1646/4885GABRA1 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.