Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | SCN4A | P35499 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9452308 | 0.86 | TDP1 (0.49) | LMNAMAOAPTGS1ADRB2ADRB1 | |
| SCHEMBL835106 | 0.85 | LMNA (0.66) | LMNAMAOAPTGS1CYP2D6SCN4A | |
| SCHEMBL851067 | 0.85 | LMNA (0.66) | LMNAMAOAPTGS1CYP2D6SCN4A | |
| SCHEMBL851069 | 0.85 | LMNA (0.66) | LMNAMAOAPTGS1CYP2D6SCN4A | |
| SCHEMBL12869056 | 0.85 | LMNA (0.70) | LMNAMAOAPTGS1CYP2D6SCN4A | |
| SCHEMBL11096227 | 0.84 | SLC6A2 (0.51) | LMNAPTGS1CYP2D6ADRB2ADRB1 | |
| SCHEMBL8187180 | 0.81 | LMNA (0.70) | LMNAMAOAPTGS1CYP2D6SCN4A | |
| SCHEMBL9564637 | 0.80 | LMNA (0.68) | LMNAMAOAPTGS1CYP2D6SCN4A | |
| SCHEMBL7268804 | 0.79 | LMNA (0.58) | LMNAMAOAPTGS1CYP2D6SCN4A | |
| Hydrochloric Acid SCHEMBL7428095 | 0.78 | LMNA (0.56) | LMNAMAOAPTGS1CYP2D6SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193227-B1 | PROCESS FOR THE PREPARATION OF ARYLGLYCIDYL ETHERS AND 3-SUBSTITUTED 1-ALKYLAMINO-2-PROPANOLS | GIST-BROCADES N.V. (NL) | 1990-04-11 | — | — | EP | disclosed |
| EP-0193227-A1 | Process for the preparation of arylglycidyl ethers and 3-substituted 1-alkylamino-2-propanols | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | disclosed |