SCHEMBL10345898

SCHEMBL10345898

CC(O)[C@H]1C(=O)N([Si](C)(C)C(C)(C)C)[C@@H]1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10865959 1.00 ELANE (0.31) ELANE
SCHEMBL10530255 0.81 ELANE (0.33) ELANE
SCHEMBL10834467 0.79 MEN1 (0.30)
SCHEMBL10416128 0.79 ELANE (0.32) ELANE
SCHEMBL11099945 0.78
SCHEMBL3332425 0.77
SCHEMBL4696518 0.77
SCHEMBL7402592 0.76 MME (0.31)
SCHEMBL9179539 0.74 FAAH (0.32) ELANE
SCHEMBL9179549 0.74 FAAH (0.32) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0171159-B1 SUBSTITUTED AZETIDINONE COMPOUNDS, THEIR PREPARATION, AND MEDICAMENTS CONTAINING THEM YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1990-05-30 EP disclosed
EP-0171159-A1 Substituted azetidinone compounds, their preparation, and medicaments containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1986-02-12 EP disclosed