Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346941 | 0.84 | CYP2C19 (0.53) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| SCHEMBL10346356 | 0.84 | SMN1; SMN2 (0.45) | MEN1KMT2AKDM4EPOLBLMNA | |
| SCHEMBL10346637 | 0.82 | KMT2A (0.41) | MEN1KMT2ALMNATP53CYP2C19 | |
| SCHEMBL10346640 | 0.80 | CYP2C19 (0.50) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 | |
| SCHEMBL10346384 | 0.80 | KMT2A (0.42) | MEN1KMT2ALMNATP53CYP2C19 | |
| SCHEMBL9622243 | 0.79 | CYP4F2 (0.40) | MEN1KMT2ALMNATP53CYP2C19 | |
| SCHEMBL10346408 | 0.79 | KMT2A (0.43) | MEN1KMT2ALMNATP53CYP2C19 | |
| SCHEMBL10346397 | 0.79 | MEN1 (0.50) | MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL10346622 | 0.78 | MEN1 (0.40) | MEN1KMT2ALMNATP53CYP2C19 | |
| SCHEMBL9563644 | 0.78 | CPT1B (0.47) | CHRM2OPRK1CYP1A2SLC6A4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728650-A | ANTIULCER, ANTITUSSIVE, EXPECTORANTS | KURARAY CO., LTD. (JP) | 1988-03-01 | — | — | US | claimed |
| EP-0202580-B1 | 3,4-DIHYDROBENZOPYRAN DERIVATIVES | KURARAY CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |
| US-4728650-A | ANTIULCER, ANTITUSSIVE, EXPECTORANTS | KURARAY CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0202580-A2 | 3,4-Dihydrobenzopyran derivatives | KURARAY CO., LTD. (JP) | 1986-11-26 | — | — | EP | disclosed |