Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1B | Q92523 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563646 | 0.80 | CHRM2 (0.44) | CPT1BMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9623016 | 0.78 | CYP4F2 (0.42) | CPT1BMEN1KMT2ALMNACYP2C19 | |
| SCHEMBL10346385 | 0.78 | CHRM2 (0.45) | CPT1BMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8541237 | 0.76 | CYP2C19 (0.43) | CPT1BMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9296206 | 0.73 | CYP2C19 (0.36) | CPT1BMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9622243 | 0.72 | CYP4F2 (0.40) | MEN1KMT2ALMNACYP2C19TP53 | |
| SCHEMBL9297113 | 0.72 | CHRM2 (0.45) | CPT1BMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9015966 | 0.72 | CPT1B (0.58) | CPT1BMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5319031 | 0.71 | CHRM2 (0.65) | CPT1BMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10346941 | 0.71 | CYP2C19 (0.53) | MEN1KMT2AALDH1A1KDM4ECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533579-A1 | Trimetazidine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-24 | — | — | EP | disclosed |