Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830725 | 0.77 | CASR (0.36) | ALDH1A1 | |
| SCHEMBL793949 | 0.74 | SLC6A2 (0.44) | SLC6A4SLC6A2KMT2ASLC6A3 | |
| SCHEMBL2088976 | 0.72 | HRH1 (0.56) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL2031145 | 0.71 | HRH1 (0.60) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL29669692 | 0.71 | HRH1 (0.60) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL30083973 | 0.71 | HRH1 (0.55) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL45176 | 0.71 | HRH1 (0.55) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL28358211 | 0.70 | THRB (0.46) | KMT2AALDH1A1 | |
| SCHEMBL28044355 | 0.70 | FFAR1 (0.65) | HRH1SLC6A4SLC6A2RIPK1CYP19A1 | |
| SCHEMBL3291158 | 0.69 | SLC6A4 (0.39) | SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220810-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-02 | — | — | EP | disclosed |