Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034717 | 1.00 | PTGER4 (0.56) | PTGER4PTGER2PTGER3 | |
| SCHEMBL1034719 | 1.00 | PTGER4 (0.56) | PTGER4PTGER2PTGER3 | |
| SCHEMBL1038223 | 0.91 | PTGER4 (0.47) | PTGER4PTGER2PTGER3 | |
| SCHEMBL1038224 | 0.91 | PTGER4 (0.47) | PTGER4PTGER2PTGER3 | |
| SCHEMBL1038222 | 0.91 | PTGER4 (0.47) | PTGER4PTGER2PTGER3 | |
| SCHEMBL6167001 | 0.88 | PTGER4 (0.62) | PTGER4PTGER2PTGER3 | |
| SCHEMBL14775778 | 0.88 | PTGER4 (0.62) | PTGER4PTGER2PTGER3 | |
| SCHEMBL6166998 | 0.88 | PTGER4 (0.62) | PTGER4PTGER2PTGER3 | |
| SCHEMBL1035813 | 0.84 | PTGER4 (0.78) | PTGER4PTGER2PTGER3 | |
| SCHEMBL1035815 | 0.84 | PTGER4 (0.78) | PTGER4PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638936-B1 | 3-OXA-8-AZAPROSTAGLANDIN ANALOGS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN INC (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-1638936-A1 | 3-OXA-8-AZAPROSTAGLANDIN ANALOGS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | Allergan, Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004108670-A1 | 3-OXA-8-AZAPROSTAGLANDIN ANALOGS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN, INC. (US) | 2004-12-16 | — | — | WO | disclosed |
| US-6734206-B1 | POTENT OCULAR HYPOTENSIVES THAT ARE PARTICULARLY SUITED FOR THE MANAGEMENT OF GLAUCOMA | ALLERGAN, INC. | 2004-05-11 | — | — | US | disclosed |