SCHEMBL14775778

SCHEMBL14775778

O=C(O)CCCCCCN1C(=O)CCC1/C=C/C(=O)Cc1cccc(Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 15/20 0.62
PTGER2 P43116 7/20 0.62
PTGER3 P43115 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6166998 1.00 PTGER4 (0.62) PTGER4PTGER2PTGER3
SCHEMBL6167001 1.00 PTGER4 (0.62) PTGER4PTGER2PTGER3
SCHEMBL6159872 0.89 PTGER4 (0.69) PTGER4PTGER2PTGER3
SCHEMBL6159877 0.89 PTGER4 (0.69) PTGER4PTGER2PTGER3
SCHEMBL1034719 0.88 PTGER4 (0.56) PTGER4PTGER2PTGER3
SCHEMBL1034718 0.88 PTGER4 (0.56) PTGER4PTGER2PTGER3
SCHEMBL1034717 0.88 PTGER4 (0.56) PTGER4PTGER2PTGER3
SCHEMBL6685848 0.88 PTGER4 (0.49) PTGER4PTGER2PTGER3
SCHEMBL6686571 0.88 PTGER4 (0.49) PTGER4PTGER2PTGER3
SCHEMBL14775789 0.88 PTGER4 (0.49) PTGER4PTGER2PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1503984-B1 8-AZAPROSTAGLANDIN ANALOGS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE ALLERGAN INC (US) 2013-03-20 EP disclosed