Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347440 | 0.96 | ITGB3 (0.38) | ITGB3ITGA2BKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10347442 | 0.96 | ITGB3 (0.38) | ITGB3ITGA2BKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10347176 | 0.95 | KMT2A (0.38) | ITGB3ITGA2BKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10347172 | 0.95 | KMT2A (0.40) | ITGB3ITGA2BKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10347175 | 0.95 | KMT2A (0.40) | ITGB3ITGA2BKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10347171 | 0.95 | KMT2A (0.38) | ITGB3ITGA2BKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10347173 | 0.95 | KMT2A (0.40) | ITGB3ITGA2BKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10347174 | 0.95 | KMT2A (0.38) | ITGB3ITGA2BKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10347427 | 0.95 | KMT2A (0.38) | ITGB3ITGA2BKMT2ASMN1; SMN2RAB9A | |
| SCHEMBL10347426 | 0.95 | KMT2A (0.38) | ITGB3ITGA2BKMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365641-A1 | PYRIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |
| WO-1989010356-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-02 | — | — | WO | disclosed |