Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347191 | 1.00 | PKM (0.36) | PKMITGB3ITGA2BIDH1KMT2A | |
| SCHEMBL10347194 | 1.00 | PKM (0.36) | PKMITGB3ITGA2BIDH1KMT2A | |
| SCHEMBL10347405 | 0.97 | KMT2A (0.36) | ITGB3ITGA2BKMT2AMAPTMEN1 | |
| SCHEMBL10347404 | 0.97 | KMT2A (0.36) | ITGB3ITGA2BKMT2AMAPTMEN1 | |
| SCHEMBL10347408 | 0.97 | KMT2A (0.36) | ITGB3ITGA2BKMT2AMAPTMEN1 | |
| SCHEMBL10347140 | 0.97 | PKM (0.38) | PKMITGB3ITGA2BIDH1KMT2A | |
| SCHEMBL10347141 | 0.97 | PKM (0.38) | PKMITGB3ITGA2BIDH1KMT2A | |
| SCHEMBL10347176 | 0.93 | KMT2A (0.38) | ITGB3ITGA2BKMT2AMAPTMEN1 | |
| SCHEMBL10347175 | 0.93 | KMT2A (0.40) | ITGB3ITGA2BIDH1KMT2AMAPT | |
| SCHEMBL10347174 | 0.93 | KMT2A (0.38) | ITGB3ITGA2BKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365641-A1 | PYRIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |
| WO-1989010356-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-02 | — | — | WO | disclosed |