Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347524 | 1.00 | KMT2A (0.36) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL10347523 | 1.00 | KMT2A (0.36) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL10347339 | 0.96 | KMT2A (0.38) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL10347338 | 0.96 | KMT2A (0.38) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL10347378 | 0.93 | KMT2A (0.36) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL10347380 | 0.93 | KMT2A (0.36) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL10347379 | 0.93 | KMT2A (0.36) | KMT2ASMN1; SMN2ESR1HIF1ARECQL | |
| SCHEMBL10347399 | 0.91 | KMT2A (0.36) | KMT2AMAPTRAB9ACYP19A1HCRTR1 | |
| SCHEMBL10347400 | 0.91 | KMT2A (0.36) | KMT2AMAPTRAB9ACYP19A1HCRTR1 | |
| SCHEMBL10347402 | 0.91 | KMT2A (0.36) | KMT2AMAPTRAB9ACYP19A1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365641-A1 | PYRIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |
| WO-1989010356-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-02 | — | — | WO | disclosed |