⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13646757 | 0.92 | — | — | |
| SCHEMBL10239814 | 0.85 | — | — | |
| SCHEMBL15623932 | 0.82 | ALDH1A1 (0.35) | — | |
| SCHEMBL14447118 | 0.82 | — | — | |
| SCHEMBL18755401 | 0.82 | TSHR (0.31) | — | |
| SCHEMBL15959325 | 0.82 | TSHR (0.31) | — | |
| SCHEMBL18400244 | 0.82 | TSHR (0.31) | — | |
| SCHEMBL18755450 | 0.82 | TSHR (0.31) | — | |
| SCHEMBL18755380 | 0.82 | TSHR (0.31) | — | |
| SCHEMBL14048422 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962146-A | 3-O-glycosyl 16-membered macrolide antibacterials and related derivatives | SCHERING CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0362267-A1 | 3-O-GLYCOSYL 16-MEMBERED MACROLIDE ANTIBACTERIALS AND RELATED DERIVATIVES | SCHERING CORPORATION (US) | 1990-04-11 | — | — | EP | disclosed |
| WO-1988008426-A1 | 3-O-GLYCOSYL 16-MEMBERED MACROLIDE ANTIBACTERIALS AND RELATED DERIVATIVES | SCHERING CORPORATION (US) | 1988-11-03 | — | — | WO | disclosed |