SCHEMBL10348246

SCHEMBL10348246

NC(=O)c1cccc2[nH]nnc12.[Ag]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 18/20 0.54
PKN1 Q16512 2/20 0.46
PKN2 Q16513 2/20 0.46
PLK4 O00444 1/20 0.46
MAPK13 O15264 1/20 0.46
DYRK3 O43781 1/20 0.46
ROCK2 O75116 1/20 0.46
RPS6KA5 O75582 1/20 0.46
PRKD3 O94806 1/20 0.46
MAP4K4 O95819 1/20 0.46
CHEK2 O96017 1/20 0.46
PIM1 P11309 1/20 0.46
PHKG2 P15735 1/20 0.46
PRKACA P17612 1/20 0.46
RPS6KB1 P23443 1/20 0.46
CSNK1D P48730 1/20 0.46
CLK2 P49760 1/20 0.46
GSK3A P49840 1/20 0.46
PRKX P51817 1/20 0.46
PRKCZ Q05513 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1698316 0.98 PARP1 (0.56) PARP1PKN1PKN2PLK4MAPK13
SCHEMBL30056390 0.98 PARP1 (0.56) PARP1PKN1PKN2PLK4MAPK13
SCHEMBL9172345 0.84 KDM4E (0.46) PARP1DHODH
SCHEMBL17584109 0.84 PARP1 (0.46) PARP1PKN1PKN2PLK4MAPK13
SCHEMBL2188295 0.84 PARP1 (0.39) PARP1PKN1PKN2PLK4MAPK13
SCHEMBL10347683 0.83 KDM4E (0.45) PARP1DHODH
Ammonia Solution, Strong SCHEMBL11038589 0.83 KDM4E (0.45) PARP1DHODH
SCHEMBL170674 0.82 KDM4E (0.47) PARP1DHODH
SCHEMBL29453826 0.82 KDM4E (0.47) PARP1DHODH
SCHEMBL4813379 0.82 PARP1 (0.38) PARP1PKN1PKN2PLK4MAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136142-B1 THERMALLY DEVELOPABLE, LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1990-04-11 EP disclosed
US-4584267-A SILVER HALIDE, SILVER SALT, REDUCING AGENT, AND BINDER OF GELATIN OR DERIVATIVE AND POLYVINYL ALCOHOL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-22 US disclosed
US-4543309-A BENZOTRIAZOLE SILVER SALT, REDUCING AGENT, BINDER, AMINO-MERCAPTO TRIAZOLE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-24 US disclosed
EP-0136142-A2 Thermally developable, light-sensitive material KONICA CORPORATION (JP) 1985-04-03 EP disclosed