SCHEMBL10348337

SCHEMBL10348337

O=C(Nc1cccc(F)c1C(=O)O)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.64
NPC1 O15118 2/20 0.64
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
PLK1 P53350 1/20 0.62
PLK3 Q9H4B4 1/20 0.62
HDAC1 Q13547 3/20 0.57
HDAC3 O15379 1/20 0.57
MAPK1 P28482 1/20 0.57
HDAC2 Q92769 1/20 0.57
GAA P10253 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
MDM4 O15151 1/20 0.53
TP53 P04637 1/20 0.53
POLB P06746 1/20 0.53
HPGD P15428 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2291449 0.87 PLK1 (0.57) RAB9ANPC1MEN1KMT2APLK1
SCHEMBL2113824 0.84 RAB9A (0.86) RAB9ANPC1MEN1KMT2AHDAC1
SCHEMBL29429740 0.84 RAB9A (0.86) RAB9ANPC1MEN1KMT2AHDAC1
SCHEMBL6762655 0.83 RAB9A (0.68) RAB9ANPC1MEN1KMT2AHDAC1
SCHEMBL20707202 0.83 KDM4E (0.49) RAB9ANPC1MEN1KMT2APLK1
SCHEMBL10348579 0.82 RAB9A (0.55) RAB9ANPC1MEN1KMT2APLK1
SCHEMBL1360439 0.82 HDAC1 (0.55) RAB9ANPC1MEN1KMT2AHDAC1
SCHEMBL29083338 0.81 RAB9A (0.66) RAB9ANPC1MEN1KMT2AHDAC1
SCHEMBL7832216 0.81 MEN1 (0.68) RAB9ANPC1MEN1KMT2AHDAC1
SCHEMBL10743969 0.80 PLK1 (0.62) RAB9ANPC1MEN1KMT2APLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0120352-B1 DERIVATIVES OF N-ACYLANTHRANILIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING WEEDS BASF Aktiengesellschaft (DE) 1990-06-13 EP claimed
EP-0120352-B1 DERIVATIVES OF N-ACYLANTHRANILIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING WEEDS BASF Aktiengesellschaft (DE) 1990-06-13 EP disclosed
EP-0120352-A1 Derivatives of N-acylanthranilic acids, process for their preparation and their use in combating weeds BASF Aktiengesellschaft (DE) 1984-10-03 EP disclosed