Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10348481 | 0.81 | LMNA (0.42) | LMNATSHRALDH1A1 | |
| SCHEMBL10348482 | 0.77 | LMNA (0.44) | LMNAALDH1A1 | |
| SCHEMBL9779354 | 0.71 | LMNA (0.42) | LMNATSHRALDH1A1 | |
| SCHEMBL6324974 | 0.70 | LMNA (0.41) | LMNAALDH1A1 | |
| SCHEMBL19353730 | 0.67 | LMNA (0.38) | LMNATSHRALDH1A1 | |
| Acetic Acid SCHEMBL10567069 | 0.65 | LMNA (0.37) | LMNAALDH1A1 | |
| SCHEMBL9069994 | 0.64 | — | — | |
| SCHEMBL8605764 | 0.62 | — | — | |
| SCHEMBL8921849 | 0.62 | LMNA (0.48) | LMNATSHRALDH1A1 | |
| SCHEMBL1700920 | 0.62 | LMNA (0.48) | LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257251-B1 | FLUOROALKYLATED DIMETHYLOLNITROMETHANES, PROCESS FOR THEIR MANUFACTURE AND THEIR APPLICATION | BAYER AG (DE) | 1990-07-11 | — | — | EP | disclosed |
| EP-0257251-A1 | Fluoroalkylated dimethylolnitromethanes, process for their manufacture and their application | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |