Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20707223 | 1.00 | MAPT (0.38) | MAPTPOLBAPLNRRECQLCYP2C19 | |
| SCHEMBL125826 | 0.78 | POLB (0.36) | MAPTPOLBAPLNRAKR1C3AKR1C1 | |
| SCHEMBL13242149 | 0.77 | MAPT (0.34) | MAPTPOLBAPLNRCYP2C19GAA | |
| SCHEMBL10595119 | 0.77 | POLB (0.42) | MAPTPOLBAPLNRRECQL | |
| SCHEMBL180151 | 0.77 | POLB (0.35) | MAPTPOLBAPLNRAKR1C3AKR1C1 | |
| Calcium SCHEMBL29816288 | 0.77 | POLB (0.35) | MAPTPOLBAPLNRAKR1C3AKR1C1 | |
| SCHEMBL4264381 | 0.76 | CRBN (0.39) | — | |
| SCHEMBL9483336 | 0.76 | AKR1C3 (0.37) | MAPTPOLBCYP2C19GAAKMT2A | |
| SCHEMBL1743259 | 0.75 | TLR4 (0.32) | MAPTPOLB | |
| SCHEMBL9788268 | 0.74 | HSD17B10 (0.50) | MAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123001-B1 | NEW CYCLOHEXANE DERIVATIVES HAVING PLANT-GROWTH REGULATING ACTIVITIES, AND USES OF THESE DERIVATIVES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-04-25 | — | — | EP | claimed |
| US-4678496-A | CROPS AND LAWNS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-07-07 | — | — | US | claimed |
| EP-0123001-A1 | New cyclohexane derivatives having plant-growth regulating activities, and uses of these derivatives | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-10-31 | — | — | EP | claimed |
| CN-1185202-C | Process for preparation of acylated 1,3-dicarbonyl compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2005-01-19 | — | — | CN | disclosed |
| CN-1368947-A | Process for preparation of acylated 1,3-dicarbonyl compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2002-09-11 | — | — | CN | disclosed |
| US-4866201-A | CYCLIZATION ACETONYLSUCCINIC ACID ESTER; REACTING WITH ORGANIC ACID CHLORIDE; THEN REARRANGEMENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| US-4678496-A | CROPS AND LAWNS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-07-07 | — | — | US | disclosed |
| US-4560403-A | Cyclohexane derivatives having plant-growth regulating activities, and uses of these derivatives | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1985-12-24 | — | — | US | disclosed |
| EP-0123001-A1 | New cyclohexane derivatives having plant-growth regulating activities, and uses of these derivatives | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |