⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10326020 | 0.97 | TSHR (0.40) | — | |
| SCHEMBL122772 | 0.85 | — | — | |
| SCHEMBL9492835 | 0.85 | TSHR (0.50) | — | |
| SCHEMBL30433623 | 0.82 | TSHR (0.48) | — | |
| SCHEMBL31324014 | 0.82 | TSHR (0.48) | — | |
| SCHEMBL30432627 | 0.82 | TSHR (0.48) | — | |
| SCHEMBL30500731 | 0.82 | TSHR (0.48) | — | |
| SCHEMBL12360400 | 0.82 | TSHR (0.48) | — | |
| SCHEMBL22589673 | 0.82 | TSHR (0.48) | — | |
| SCHEMBL15803984 | 0.82 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |
| US-10017527-B2 | KLK4 inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2018-07-10 | — | — | US | disclosed |
| US-20170101427-A1 | NOVEL KLK4 INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2017-04-13 | — | — | US | disclosed |
| EP-3122758-A1 | NOVEL KLK4 INHIBITORS | Universiteit Antwerpen (BE) | 2017-02-01 | — | — | EP | disclosed |
| WO-2015144933-A1 | NOVEL KLK4 INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2015-10-01 | — | — | WO | disclosed |
| US-20140079632-A1 | ACTIVITY-BASED PROBES FOR THE UROKINASE PLASMINOGEN ACTIVATOR | UNIVERSITEIT ANTWERPEN (BE) | 2014-03-20 | — | — | US | disclosed |
| EP-2707034-A1 | ACTIVITY-BASED PROBES FOR THE UROKINASE PLASMINOGEN ACTIVATOR | Universiteit Antwerpen (BE) | 2014-03-19 | — | — | EP | disclosed |
| WO-2012152807-A1 | ACTIVITY-BASED PROBES FOR THE UROKINASE PLASMINOGEN ACTIVATOR | UNIVERSITEIT ANTWERPEN (BE) | 2012-11-15 | — | — | WO | disclosed |
| EP-0120352-B1 | DERIVATIVES OF N-ACYLANTHRANILIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING WEEDS | BASF Aktiengesellschaft (DE) | 1990-06-13 | — | — | EP | disclosed |
| EP-0120352-A1 | Derivatives of N-acylanthranilic acids, process for their preparation and their use in combating weeds | BASF Aktiengesellschaft (DE) | 1984-10-03 | — | — | EP | disclosed |