SCHEMBL9492835

SCHEMBL9492835

C#CCOCCOCC#C

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27190031 0.96 TSHR (0.48) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL15803986 0.96 TSHR (0.48) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL22589673 0.96 TSHR (0.48) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL31324014 0.96 TSHR (0.48) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL15803984 0.96 TSHR (0.48) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL15800508 0.96 TSHR (0.48) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL12360400 0.96 TSHR (0.48) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL17186655 0.86 TSHR (0.58) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL7254965 0.86 TSHR (0.58) TSHRPOLBMAPK1HSD17B10MEN1
SCHEMBL25234596 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119620537-A Photosensitive polyimide photoresist and preparation method thereof 中山大学 2025-03-14 CN claimed
CN-119620537-A Photosensitive polyimide photoresist and preparation method thereof 中山大学 2025-03-14 CN disclosed
EP-4519340-A1 PROCESS FOR PREPARING A POLYCARBONATE BY METAL CATALYZED CROSS COUPLING Covestro Deutschland AG (DE) 2025-03-12 EP disclosed
US-20250059221-A1 STAT DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-02-20 US disclosed
WO-2025010326-A2 DIMERIC IMMUNO-MODULATORY COMPOUNDS AGAINST CEREBLON-BASED MECHANISMS H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2025-01-09 WO disclosed
CN-119137182-A Method for producing polycarbonates by metal-catalyzed cross-coupling 科思创德国股份有限公司 2024-12-13 CN disclosed
CN-118772376-A Radically polymerizable adhesion-promoting interlayer compositions and methods of use PRC-迪索托国际公司 2024-10-15 CN disclosed
US-12077555-B2 STAT degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2024-09-03 US disclosed
US-12023323-B2 Carbohydrate-binding small molecules with antiviral activity RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) 2024-07-02 US disclosed
US-20240199911-A1 HYBRID DUAL CURE COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2024-06-20 US disclosed
US-20140323422-A1 Anionic Conjugates of Glycosylated Bacterial Metabolite Glycosynnovations Pty Ltd (AU) 2014-10-30 US disclosed
US-8791245-B2 Anionic conjugates of glycosylated bacterial metabolite Glycan Bioscience LLC (US) 2014-07-29 US disclosed
US-8791245-B2 Anionic conjugates of glycosylated bacterial metabolite Glycan Bioscience LLC (US) 2014-07-29 US disclosed
US-20140171536-A1 Dental Restorative Materials Based on Polymerizable Azides and Alkynes IVOCLAR VIVADENT AG (LI) 2014-06-19 US disclosed
EP-2743267-A1 Dental materials based on polymerisable azides and alkenes Ivoclar Vivadent AG (LI) 2014-06-18 EP disclosed
US-20110190233-A1 ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE GLYCAN BIOSCIENCES PTY LTD (AU) 2011-08-04 US disclosed
US-20110190233-A1 ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE GLYCAN BIOSCIENCES PTY LTD (AU) 2011-08-04 US disclosed
US-20100303754-A1 PROCESS FOR PREPARATION OF CYCLODEXTRIN OLIGOMERS OR POLYMERS, PRODUCTS OBTAINED AND USES BIOCYDEX (FR) 2010-12-02 US disclosed
WO-2010037179-A1 ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE GLYCAN BIOSCIENCES PTY LTD (AU) 2010-04-08 WO disclosed
US-5264112-A Acidic nickel baths containing 1-(2-sulfoethyl)-pyridiniumbetaine ATOTECH DEUTSCHLAND GMBH (DE) 1993-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110190233-A1 ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE GNE, CD44, FUT5 TSHR 3687/4885POLB 2247/4885MAPK1 2080/4885
US-12077555-B2 STAT degraders and uses thereof STAT4, STAT1, STAT3 TSHR 1768/4885POLB 1265/4885MAPK1 3754/4885
US-20140323422-A1 Anionic Conjugates of Glycosylated Bacterial Metabolite GNE, CD44, FUT5 TSHR 3687/4885POLB 2247/4885MAPK1 2080/4885
US-12023323-B2 Carbohydrate-binding small molecules with antiviral activity HAVCR2, GALE, ZC3HAV1 TSHR 4782/4885POLB 1620/4885MAPK1 3003/4885
US-20250059221-A1 STAT DEGRADERS AND USES THEREOF STAT4, STAT1, STAT3 TSHR 1768/4885POLB 1265/4885MAPK1 3754/4885
US-20100303754-A1 PROCESS FOR PREPARATION OF CYCLODEXTRIN OLIGOMERS OR POLYMERS, PRODUCTS OBTAINED AND USES ALG1, OSTC, ALG8 TSHR 3946/4885POLB 1987/4885MAPK1 3180/4885
US-20140171536-A1 Dental Restorative Materials Based on Polymerizable Azides and Alkynes PRXL2A, CNPY2, CDYL TSHR 3177/4885POLB 3253/4885MAPK1 3088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.