Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10348458 | 0.97 | TRPV1 (0.68) | TRPV1KDM4EMEN1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL10348748 | 0.97 | TRPV1 (0.68) | TRPV1KDM4EMEN1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL10348701 | 0.85 | TRPV1 (0.53) | TRPV1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL30125341 | 0.83 | TRPV1 (0.64) | TRPV1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL1413170 | 0.83 | TRPV1 (0.64) | TRPV1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL2676769 | 0.81 | TRPV1 (0.70) | TRPV1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL13151456 | 0.81 | TRPV1 (1.00) | TRPV1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL5957878 | 0.80 | ALDH1A1 (0.68) | KDM4EMEN1MAPTRAB9AKMT2A | |
| SCHEMBL30125017 | 0.80 | TRPV1 (0.70) | TRPV1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL1413214 | 0.80 | TRPV1 (0.70) | TRPV1KDM4EMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141377-B1 | METAL COMPLEXES | HODOGAYA CHEMICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |