Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689655 | 0.92 | HSP90AA1 (0.36) | HSP90AA1GRM5DHFRLCKJAK3 | |
| SCHEMBL10307332 | 0.92 | HSP90AA1 (0.36) | HSP90AA1GRM5DHFRLCKJAK3 | |
| SCHEMBL10392527 | 0.85 | HRH3 (0.37) | JAK3NOS2 | |
| SCHEMBL29365049 | 0.85 | HRH3 (0.37) | JAK3NOS2 | |
| SCHEMBL7115020 | 0.83 | MEN1 (0.39) | DHFR | |
| SCHEMBL7116397 | 0.81 | KCNH2 (0.40) | DHFR | |
| SCHEMBL8053438 | 0.78 | HSP90AA1 (0.37) | HSP90AA1GRM5DHFRLCKNOS2 | |
| SCHEMBL5230567 | 0.77 | MAPKAPK2 (0.40) | HSP90AA1DHFR | |
| SCHEMBL29364752 | 0.76 | HSP90AA1 (0.36) | HSP90AA1DHFRLCKJAK3NOS2 | |
| SCHEMBL7156533 | 0.76 | HSP90AA1 (0.36) | HSP90AA1DHFRLCKJAK3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363532-A1 | Process for preparing pyrazines from hydroxyamines | TEXACO DEVELOPMENT CORPORATION (US) | 1990-04-18 | — | — | EP | disclosed |