Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115020 | 0.98 | MEN1 (0.39) | KCNH2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29365049 | 0.92 | HRH3 (0.37) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL10392527 | 0.92 | HRH3 (0.37) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7114777 | 0.85 | KCNH2 (0.40) | KCNH2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2512668 | 0.85 | KCNH2 (0.40) | KCNH2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10307332 | 0.84 | HSP90AA1 (0.36) | ALDH1A1KDM4EDHFR | |
| SCHEMBL30689655 | 0.84 | HSP90AA1 (0.36) | ALDH1A1KDM4EDHFR | |
| SCHEMBL7115027 | 0.83 | MEN1 (0.39) | KCNH2MEN1KMT2AALDH1A1MAPT | |
| Pyrazine SCHEMBL10348783 | 0.81 | HSP90AA1 (0.33) | DHFR | |
| SCHEMBL11332526 | 0.78 | KCNH2 (0.45) | KCNH2MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357193-A1 | Preparation of pyrazines | SOCIETE DES PRODUITS NESTLE S.A. (CH) | 2003-10-29 | — | — | EP | disclosed |