Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639706 | 1.00 | TSHR (0.62) | TSHRDNM1MEN1KMT2AALDH1A1 | |
| Butylamine SCHEMBL3285128 | 0.93 | TSHR (0.56) | TSHRALDH1A1THRBCYP1A2FAAH | |
| Decane SCHEMBL27941727 | 0.91 | TSHR (0.74) | TSHRMEN1KMT2AALDH1A1THRB | |
| Hexadecane SCHEMBL28334360 | 0.89 | TSHR (0.71) | TSHRMEN1KMT2AALDH1A1THRB | |
| Propylamine SCHEMBL3280862 | 0.87 | THRB (0.53) | TSHRALDH1A1THRBCYP1A2 | |
| Hexadecylamine SCHEMBL28387490 | 0.86 | TSHR (0.74) | TSHRDNM1MEN1KMT2AALDH1A1 | |
| Ethylenediamine SCHEMBL4650024 | 0.85 | THRB (0.61) | TSHRALDH1A1THRBCYP1A2 | |
| SCHEMBL9518387 | 0.84 | TSHR (0.89) | TSHRALDH1A1EPHX1THRBFAAH | |
| SCHEMBL17435240 | 0.84 | TSHR (0.89) | TSHRALDH1A1EPHX1THRBFAAH | |
| Ethylamine SCHEMBL4364175 | 0.82 | THRB (0.57) | TSHRALDH1A1THRBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187137-B1 | COLORED CONTACT LENSES AND METHOD FOR MAKING SAME | SCHERING CORPORATION (US) | 1990-07-11 | — | — | EP | disclosed |
| US-4668240-A | COATING POLYMER LENS WITH COLORANT, BINDER POLYMER; ISOCYANATES, EPOXIDES | SCHERING CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0187137-A2 | Colored contact lenses and method for making same | SCHERING CORPORATION (US) | 1986-07-09 | — | — | EP | disclosed |