SCHEMBL10349394

SCHEMBL10349394

O=c1ccn(C2CCC(CO)O2)c(=O)[nH]1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 0.52
▸ SLC28A2 O43868 1/20 0.52
▸ SLC29A1 Q99808 1/20 0.52
▸ SLC28A3 Q9HAS3 1/20 0.52
▸ ABL1 P00519 1/20 0.46
▸ RIN1 Q13671 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ ALB P02768 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ DUT P33316 3/20 0.43
▸ P2RY2 P41231 7/20 0.41
▸ P2RY6 Q15077 4/20 0.39
▸ P2RY4 P51582 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30007720 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3ABL1
SCHEMBL28067259 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3ABL1
SCHEMBL543110 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3ABL1
SCHEMBL22110849 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3ABL1
SCHEMBL23254274 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3ABL1
SCHEMBL8715 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3ABL1
SCHEMBL23254269 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3ABL1
SCHEMBL24695426 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3ABL1
SCHEMBL22110735 1.00 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3ABL1
Hydrochloric Acid SCHEMBL27275372 0.99 SLC28A1 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024129985-A2 ANTIVIRAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. (US) 2024-06-20 — — WO disclosed
WO-2023183569-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2023-09-28 — — WO disclosed
WO-2023142803-A1 ANTIVIRAL COMPOUND AND USE THEREOF 北京恩泰伟医药科技有限公司 2023-08-03 — — WO disclosed
WO-2023142803-A1 ANTIVIRAL COMPOUND AND USE THEREOF 北京恩泰伟医药科技有限公司 2023-08-03 — — WO disclosed
WO-2023113038-A1 OLIGONUCLEOTIDE PRODUCTION METHOD リードファーマ株式会社 2023-06-22 — — WO disclosed
EP-3131914-B1 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS LLC (US) 2023-05-10 — — EP disclosed
WO-2023004130-A1 METHODS FOR PREPARING BISPHOSPHOCINS Lakewood Amedex, Inc. (US) 2023-01-26 — — WO disclosed
WO-2022133205-A1 SYNTHESIS OF ANTIVIRAL NUCLEOSIDES MERCK SHARP & DOHME CORP. (US) 2022-06-23 — — WO disclosed
WO-2022035917-A1 SYNTHESIS OF FLUORINATED NUCLEOTIDES MERCK SHARP & DOHME CORP. (US) 2022-02-17 — — WO disclosed
EP-3888693-A1 DRUG DELIVERY SYSTEM USING SOLUTION Kyoto University (JP) 2021-10-06 — — EP disclosed
EP-3533873-A1 MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS Translate Bio MA, Inc. (US) 2019-09-04 — — EP disclosed
WO-2019071028-A1 NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF AVIDITY BIOSCIENCES LLC (US) 2019-04-11 — — WO disclosed
EP-2756080-B1 MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS TRANSLATE BIO MA INC (US) 2019-02-20 — — EP disclosed
US-20180207160-A1 THYMINE DERIVATIVES AND QUINAZOLINE-DIONE DERIVATIVES FOR THE INHIBITION OF HSP27 TECHNISCHE UNIVERSITAET DRESDEN (DE) 2018-07-26 — — US disclosed
EP-2958998-B1 SHORT INTERFERING NUCLEIC ACID (SINA) MOLECULES CONTAINING A 2' INTERNUCLEOSIDE LINKAGE SIRNA THERAPEUTICS INC (US) 2017-12-27 — — EP disclosed
US-20170216297-A1 EFFICIENT INHIBITION OF HSP27 TECHNISCHE UNIVERSITAET DRESDEN (DE) 2017-08-03 — — US disclosed
US-20170216297-A1 EFFICIENT INHIBITION OF HSP27 TECHNISCHE UNIVERSITAET DRESDEN (DE) 2017-08-03 — — US disclosed
US-20120184457-A1 Modulation of miRNA Activity CAMBRIDGE ENTERPRISE LIMITED (GB) 2012-07-19 — — US disclosed
US-20120184457-A1 Modulation of miRNA Activity CAMBRIDGE ENTERPRISE LIMITED (GB) 2012-07-19 — — US disclosed
WO-2011015829-A1 MODULATION OF MIRNA ACTIVITY CAMBRIDGE ENTERPRISE LIMITED (GB) 2011-02-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180207160-A1 THYMINE DERIVATIVES AND QUINAZOLINE-DIONE DERIVATIVES FOR THE INHIBITION OF HSP27 HSPB1, HSP90B1, HSP90AB1 SLC28A1 1280/4885SLC28A2 2488/4885SLC29A1 1512/4885
US-20170216297-A1 EFFICIENT INHIBITION OF HSP27 HSPB1, HSP90AB2P, HSP90B1 SLC28A1 182/4885SLC28A2 138/4885SLC29A1 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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