SCHEMBL10349396

SCHEMBL10349396

c1ccc2c(c1)c1ccccc1n2-c1ccc2sc3ccc(-c4ccc5oc6ccc(-c7ccc8sc9ccc(-n%10c%11ccccc%11c%11ccccc%11%10)cc9c8c7)cc6c5c4)cc3c2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PLA2G2A P14555 3/20 0.33
PLA2G4A P47712 3/20 0.33
CASP3 P42574 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
PLA2G10 O15496 1/20 0.32
CHRNA7 P36544 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15781006 1.00 KDM4E (0.38) KDM4EATML3MBTL1MEN1NPC1
SCHEMBL10348780 1.00 KDM4E (0.38) KDM4EATML3MBTL1MEN1NPC1
SCHEMBL15780957 1.00 KDM4E (0.38) KDM4EATML3MBTL1MEN1NPC1
SCHEMBL10042921 1.00 KDM4E (0.38) KDM4EATML3MBTL1MEN1NPC1
SCHEMBL17612226 0.99 KDM4E (0.37) KDM4EATML3MBTL1MEN1NPC1
SCHEMBL24728586 0.97 KDM4E (0.36) KDM4EATML3MBTL1MEN1NPC1
SCHEMBL18588622 0.96 PLA2G2A (0.37) KDM4EATML3MBTL1MEN1NPC1
SCHEMBL10041349 0.96 PLA2G2A (0.37) KDM4EATML3MBTL1MEN1NPC1
SCHEMBL10041354 0.96 PLA2G2A (0.37) KDM4EATML3MBTL1MEN1NPC1
SCHEMBL2628336 0.96 PLA2G2A (0.39) KDM4EATML3MBTL1MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8221908-B2 Organic electroluminescent device, display, and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-07-17 US disclosed
US-8221908-B2 Organic electroluminescent device, display, and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-07-17 US disclosed
US-20110168990-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY, AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2011-07-14 US disclosed
US-20110168990-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY, AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2011-07-14 US disclosed
US-7935434-B2 Organic electroluminescent device, display, and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-05-03 US disclosed
US-20090096360-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY, AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-04-16 US disclosed