⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713386 | 0.79 | LMNA (0.33) | — | |
| SCHEMBL10149533 | 0.71 | — | — | |
| SCHEMBL9115046 | 0.71 | — | — | |
| SCHEMBL9115050 | 0.71 | — | — | |
| SCHEMBL28081467 | 0.71 | — | — | |
| SCHEMBL20535558 | 0.69 | — | — | |
| SCHEMBL10502232 | 0.68 | — | — | |
| SCHEMBL5230319 | 0.68 | LMNA (0.36) | — | |
| SCHEMBL4702245 | 0.67 | — | — | |
| SCHEMBL20856337 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369063-B | Pyrazolyl acrylonitrile compound and preparation method and application thereof | 沈阳农业大学 | 2023-09-26 | — | — | CN | claimed |
| CN-114369063-A | Pyrazolyl acrylonitrile compound and preparation method and application thereof | 沈阳农业大学 | 2022-04-19 | — | — | CN | claimed |
| CN-105801484-B | A kind of preparation method of pyrazolyl acrylonitrile compound | 沈阳中化农药化工研发有限公司 | 2018-08-07 | — | — | CN | claimed |
| CN-105801484-A | Preparation method of pyrazolyl acrylonitrile compound | 沈阳中化农药化工研发有限公司 | 2016-07-27 | — | — | CN | claimed |
| CN-103833639-B | pyrazolyl acrylonitrile compound and application thereof | SHENYANG SINOCHEM PESTICIDE CHEMICAL RESEARCH AND DEVELOPMENT CO., LTD. (CN) | 2016-05-18 | — | — | CN | claimed |
| CN-103833639-A | Pyrazolyl acrylonitrile compound and application thereof | SINOCHEM CORP | 2014-06-04 | — | — | CN | claimed |
| CN-102395566-B | Pyrazolyl acrylonitrile compounds and uses thereof | SINOCHEM CORP | 2013-12-25 | — | — | CN | claimed |
| EP-2426110-B1 | PYRAZOLYL ACRYLONITRILE COMPOUNDS AND USES THEREOF | SINOCHEM CORP (CN) | 2013-10-16 | — | — | EP | claimed |
| US-8455532-B2 | Pyrazolyl acrylonitrile compounds and uses thereof | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-06-04 | — | — | US | claimed |
| CN-102395566-A | Pyrazolyl acrylonitrile compounds and uses thereof | SINOCHEM CORP | 2012-03-28 | — | — | CN | claimed |
| EP-2426110-A1 | PYRAZOLYL ACRYLONITRILE COMPOUNDS AND USES THEREOF | Sinochem Corporation (CN) | 2012-03-07 | — | — | EP | claimed |
| US-20120035236-A1 | Pyrazolyl Acrylonitrile Compounds and Uses Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2012-02-09 | — | — | US | claimed |
| CN-101875633-B | Pyrazolyl acrylonitrile compound and application thereof | SHENYANG RES INST CHEMICAL IND | 2012-01-18 | — | — | CN | claimed |
| CN-101875633-A | Pyrazolyl acrylonitrile compound and application thereof | SHENYANG RES INST CHEMICAL IND | 2010-11-03 | — | — | CN | claimed |
| CN-114369063-B | Pyrazolyl acrylonitrile compound and preparation method and application thereof | 沈阳农业大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-114369063-B | Pyrazolyl acrylonitrile compound and preparation method and application thereof | 沈阳农业大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-114369063-B | Pyrazolyl acrylonitrile compound and preparation method and application thereof | 沈阳农业大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-101875633-A | Pyrazolyl acrylonitrile compound and application thereof | SHENYANG RES INST CHEMICAL IND | 2010-11-03 | — | — | CN | disclosed |
| US-7622486-B2 | Pyridine compounds, process for their preparation and compositions containing them | REDDY US THERAPEUTICS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20060084644-A1 | Novel pyridine compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-20 | — | — | US | disclosed |