Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885139 | 1.00 | RAB9A (0.61) | RAB9ASMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL9435049 | 0.99 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL9435212 | 0.99 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL10349469 | 0.99 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL9435139 | 0.99 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL9435151 | 0.99 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL10000257 | 0.99 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL9330924 | 0.99 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL9435108 | 0.99 | RAB9A (0.63) | RAB9ASMN1; SMN2MAPTHSD17B10KDM4E | |
| SCHEMBL8748800 | 0.96 | RAB9A (0.57) | RAB9ASMN1; SMN2MAPTHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207975-B1 | LIQUID CRYSTALLINE PHASES | MERCK PATENT GmbH (DE) | 1990-05-16 | — | — | EP | disclosed |
| US-4818428-A | MIXTURE OF POLAR AND APOLAR COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-04-04 | — | — | US | disclosed |
| EP-0207975-A1 | LIQUID CRYSTALLINE PHASES. | MERCK PATENT GMBH (DE) | 1987-01-14 | — | — | EP | disclosed |
| WO-1986004081-A1 | LIQUID CRYSTALLINE PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-07-17 | — | — | WO | disclosed |