Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | BLM | P54132 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RECQL | P46063 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | APEX1 | P27695 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27001798 | 0.84 | ESR1 (0.39) | TDP1PTGS1 | |
| SCHEMBL9717088 | 0.80 | ALDH1A1 (0.43) | TDP1KDM4EBLMMAPTLMNA | |
| SCHEMBL28528503 | 0.79 | MAPT (0.58) | TDP1KDM4EBLMMAPTRECQL | |
| SCHEMBL13395853 | 0.78 | TDP1 (0.47) | TDP1KDM4EBLMMAPTRECQL | |
| SCHEMBL28286504 | 0.75 | BLM (0.47) | TDP1KDM4EBLMMAPTRECQL | |
| SCHEMBL15973924 | 0.75 | KDM4E (0.43) | TDP1KDM4EBLMMAPTRECQL | |
| SCHEMBL7177565 | 0.73 | TSHR (0.32) | TDP1MAPK1TSHRL3MBTL1 | |
| SCHEMBL6224690 | 0.72 | TSHR (0.43) | TDP1BLMADRB2LMNAAPEX1 | |
| SCHEMBL4422682 | 0.72 | HTR2A (0.36) | KMT2ACYP1A2 | |
| SCHEMBL6221926 | 0.71 | IDO1 (0.34) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232679-B1 | SYNTHETIC ORGANIC POLYMERS FOR THE SELECTIVE FLOCCULATION OF TITANIUM AND IRON ORES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1990-07-25 | — | — | EP | disclosed |
| US-4698171-A | Synthetic organic polymers for the selective flocculation of titanium and iron ores | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1987-10-06 | — | — | US | disclosed |