Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352194 | 0.96 | MAPT (0.56) | MAPTTHRATHRBARALDH1A1 | |
| SCHEMBL13481164 | 0.91 | MAPT (0.63) | MAPTARALDH1A1LMNA | |
| SCHEMBL15923825 | 0.82 | MAPT (0.56) | MAPTTHRATHRBPLA2G4BALDH1A1 | |
| SCHEMBL5460796 | 0.82 | AR (0.47) | MAPTARALDH1A1LMNA | |
| SCHEMBL9277559 | 0.82 | MAPT (0.61) | MAPTPLA2G4BALDH1A1LMNATLR4 | |
| SCHEMBL6716948 | 0.82 | CHRNB2 (0.54) | MAPTTHRATHRBAR | |
| SCHEMBL1608924 | 0.81 | MAPT (0.69) | MAPTPLA2G4BALDH1A1LMNA | |
| SCHEMBL1608515 | 0.81 | MAPT (0.69) | MAPTPLA2G4BALDH1A1LMNA | |
| SCHEMBL16153093 | 0.81 | MAPT (0.69) | MAPTPLA2G4BALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7327415 | 0.80 | TMEM97 (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300390-B1 | TRIFLUOROMETHYL-ALKOXY-ANILIN, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE ICE-COLOUR TECHNIQUE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0300390-A1 | Trifluoromethyl-alkoxy-anilin, process for their preparation and their use in the ice-colour technique | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-25 | — | — | EP | disclosed |