Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10352304 | 1.00 | KDR (0.62) | KDRMEN1LMNAMAPTKMT2A | |
| SCHEMBL2769400 | 0.99 | KDR (0.63) | KDRMEN1LMNAMAPTKMT2A | |
| SCHEMBL2769405 | 0.99 | KDR (0.63) | KDRMEN1LMNAMAPTKMT2A | |
| Bromide SCHEMBL2770147 | 0.98 | KDR (0.62) | KDRMEN1LMNAMAPTKMT2A | |
| Bromide SCHEMBL2773473 | 0.98 | KDR (0.62) | KDRMEN1LMNAMAPTKMT2A | |
| SCHEMBL2771487 | 0.89 | KDR (0.52) | KDR | |
| SCHEMBL2771485 | 0.89 | KDR (0.52) | KDR | |
| Bromide SCHEMBL2771712 | 0.88 | KDR (0.51) | KDR | |
| Bromide SCHEMBL2771464 | 0.88 | KDR (0.51) | KDR | |
| SCHEMBL17038721 | 0.87 | KDR (0.73) | KDRMEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178832-B1 | THERMAL TRANSFER PRINTING | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | disclosed |
| US-4664671-A | BRIGHT, GLOSSY, DENSE IMAGES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-05-12 | — | — | US | disclosed |
| EP-0178832-A2 | Thermal transfer printing | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-04-23 | — | — | EP | disclosed |