Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.54 |
| ▸ | RGS12 | O14924 | 1/20 | 0.54 |
| ▸ | PMM2 | O15305 | 1/20 | 0.54 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYBB | P04839 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30530469 | 0.74 | METAP2 (0.57) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL1353489 | 0.74 | METAP2 (0.57) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5916782 | 0.73 | METAP2 (0.61) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5916962 | 0.73 | METAP2 (0.54) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5916571 | 0.72 | METAP2 (0.54) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5916817 | 0.72 | METAP2 (0.56) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5917047 | 0.72 | METAP2 (0.56) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5916662 | 0.72 | METAP2 (0.54) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5916688 | 0.72 | MPI (0.58) | METAP2KDM4EMEN1QSOX1RGS12 | |
| SCHEMBL5916609 | 0.72 | METAP2 (0.52) | METAP2KDM4EMEN1QSOX1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257306-B1 | DISELENOBIS BENZOIC ACID AMIDES OF PRIMARY HETEROCYCLIC AMINES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOUNDS COMPRISING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1990-09-12 | — | — | EP | disclosed |
| US-4910313-A | Containing a heterocyclic ring | NATTERMANN & CIE GMBH (DE) | 1990-03-20 | — | — | US | disclosed |
| EP-0257306-A1 | Diselenobis benzoic acid amides of primary heterocyclic amines, process for producing the same and pharmaceutical compounds comprising the same | A. Nattermann & Cie. GmbH (DE) | 1988-03-02 | — | — | EP | disclosed |