Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | TNF | P01375 | 1/20 | 0.63 |
| ▸ | PDE6D | O43924 | 1/20 | 0.61 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.61 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10353601 | 0.98 | MEN1 (0.97) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL95065 | 0.89 | MEN1 (0.79) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL229324 | 0.88 | MEN1 (0.78) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL228889 | 0.88 | LMNA (0.90) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL11746981 | 0.87 | MEN1 (0.77) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL102779 | 0.87 | MEN1 (0.77) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL10353116 | 0.87 | KMT2A (0.76) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL15685952 | 0.86 | LMNA (1.00) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL10353543 | 0.85 | MEN1 (0.74) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL10877748 | 0.85 | MEN1 (0.73) | MEN1KMT2ALMNAALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507246-B | Benzimidazole substituted amino phenol oxygen zinc halide, and preparation method and application thereof | 华东理工大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-109879810-B | Imidazole ring substituted aminophenol oxygen radical zinc complex and preparation method and application thereof | 华东理工大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-114507246-A | Benzimidazole substituted aminophenoxy zinc halide and preparation method and application thereof | 华东理工大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-109879810-A | A kind of cyclosubstituted amino phenols oxygroup zinc complex of imidazoles and its preparation method and application | 华东理工大学 | 2019-06-14 | — | — | CN | disclosed |
| US-8883826-B2 | Alkynyl derivatives as modulators of metabotropic glutamate receptors | ADDEX PHARMA SA (CH) | 2014-11-11 | — | — | US | disclosed |
| US-8674106-B2 | Alkynyl derivatives as modulators of metabotropic glutamate receptors | ADDEX PHARMA SA (CH) | 2014-03-18 | — | — | US | disclosed |
| US-20130178631-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2013-07-11 | — | — | US | disclosed |
| US-20120277237-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2012-11-01 | — | — | US | disclosed |
| EP-2426115-A2 | Alkynyl derivatives as modulators of metabotropic glutamate receptors | Addex Pharma SA (CH) | 2012-03-07 | — | — | EP | disclosed |
| US-8101637-B2 | Alkynyl derivatives as modulators of metatropic glutamate receptors | ADDEX PHARMA SA (CH) | 2012-01-24 | — | — | US | disclosed |
| US-20090124625-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2009-05-14 | — | — | US | disclosed |
| EP-0252507-B1 | 2-(4-PYRIDYLAMINOMETHYL)-BENZIMIDAZOLE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | Maruishi Seiyaku Kabushiki Kaisha (JP) | 1990-10-10 | — | — | EP | disclosed |
| US-4818761-A | VIRICIDES FOR COMMON COLD, HEPATITIS, POLIOMYELITIS | MARUISHI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0252507-A1 | 2-(4-Pyridylaminomethyl)-benzimidazole derivatives having antiviral activity | Maruishi Seiyaku Kabushiki Kaisha (JP) | 1988-01-13 | — | — | EP | disclosed |
| EP-0010063-B1 | PROCESS FOR THE PREPARATION OF FURANYL-BENZAZOLES | CIBA-GEIGY AG (CH) | 1982-12-29 | — | — | EP | disclosed |
| EP-0010063-A2 | Process for the preparation of furanyl-benzazoles | CIBA-GEIGY AG (CH) | 1980-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178631-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | GRM5, GRM1, GRM2 | MEN1 4118/4885KMT2A 2181/4885LMNA 4407/4885 |
| US-20090124625-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS | GRM5, GRM2, GRM1 | MEN1 3565/4885KMT2A 1833/4885LMNA 4715/4885 |
| US-20120277237-A1 | NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | GRM5, GRM1, GRM2 | MEN1 4118/4885KMT2A 2181/4885LMNA 4407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.