Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | ATIC | P31939 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 8/20 | 0.37 |
| ▸ | CA2 | P00918 | 8/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069245 | 0.90 | CDC25A (0.52) | CDC25ACDC25BNR1H4CYP24A1CA1 | |
| SCHEMBL9010672 | 0.85 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1ATIC | |
| SCHEMBL13790493 | 0.85 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1ATIC | |
| SCHEMBL9718383 | 0.85 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1ATIC | |
| SCHEMBL14107816 | 0.85 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1ATIC | |
| SCHEMBL10041409 | 0.85 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1ATIC | |
| SCHEMBL10712009 | 0.85 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1ATIC | |
| SCHEMBL10125344 | 0.85 | CDC25A (0.49) | CDC25ACDC25BNR1H4CYP24A1ATIC | |
| SCHEMBL25314057 | 0.83 | CDC25A (0.53) | CDC25ACDC25BNR1H4CYP24A1ATIC | |
| SCHEMBL25314052 | 0.83 | CDC25A (0.53) | CDC25ACDC25BNR1H4CYP24A1ATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230600-B1 | PRODUCTION OF CHOLECALCIFEROL DERIVATIVES AND NOVEL INTERMEDIATES USED THEREFOR | Teva Pharmaceutical Industries Limited (IL) | 1990-06-27 | — | — | EP | disclosed |
| US-4758382-A | Process for the stereospecific preparation of 24(R),25- and 24(S),25-dihydroxycholecalciferol and novel intermediates used therefor | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1988-07-19 | — | — | US | disclosed |