SCHEMBL10353043

SCHEMBL10353043

C1=Nc2ccccc2OCOc2ccccc2N=1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.54
PKM P14618 2/20 0.42
TSHR P16473 1/20 0.42
LMNA P02545 5/20 0.40
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPT P10636 3/20 0.40
GAA P10253 2/20 0.40
ITGB2 P05107 1/20 0.37
ICAM1 P05362 1/20 0.37
ITGAL P20701 1/20 0.37
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
FGFR1 P11362 1/20 0.34
SMN1; SMN2 Q16637 5/20 0.33
CRHBP P24387 2/20 0.33
CRHR2 Q13324 2/20 0.33
ADORA2A P29274 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19155505 0.94 ABCG2 (0.48) ABCG2PKMTSHRLMNANPC1
SCHEMBL14802675 0.92 ABCG2 (0.44) ABCG2PKMTSHRLMNANPC1
SCHEMBL14802682 0.90 ABCG2 (0.43) ABCG2PKMTSHRLMNANPC1
SCHEMBL14802869 0.88 ABCG2 (0.42) ABCG2PKMTSHRLMNANPC1
SCHEMBL10353507 0.87 ITGB2 (0.54) ABCG2TSHRLMNANPC1RAB9A
SCHEMBL18874763 0.87 ITGB2 (0.54) ABCG2TSHRLMNANPC1RAB9A
SCHEMBL10353048 0.85 ABCG2 (0.39) ABCG2ALDH1A1L3MBTL1
SCHEMBL14802680 0.82 LMNA (0.37) ABCG2LMNANPC1RAB9AKDM4E
SCHEMBL10353054 0.82 LMNA (0.37) ABCG2LMNANPC1RAB9AKDM4E
SCHEMBL14802775 0.82 LMNA (0.44) ABCG2LMNANPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702504-B2 Resin composition for printed wiring board, prepreg, laminate, metal foil-clad laminate, printed wiring board, and multilayer printed wiring board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-07-18 US disclosed
US-9874827-B2 Electrostatic charge image developing toner, electrostatic charge image developer, and toner cartridge FUJI XEROX CO., LTD. (JP) 2018-01-23 US disclosed
US-20170261878-A1 ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, ELECTROSTATIC CHARGE IMAGE DEVELOPER, AND TONER CARTRIDGE FUJI XEROX CO., LTD. (JP) 2017-09-14 US disclosed
US-9758496-B2 Method of using a cyclic carbodiimide TEIJIN LIMITED (JP) 2017-09-12 US disclosed
US-9660119-B2 Polyester film, method for producing the same, back sheet for solar cell, and solar cell module FUJIFILM CORPORATION (JP) 2017-05-23 US disclosed
US-9650350-B2 Polylactic acid composition TEIJIN LIMITED (JP) 2017-05-16 US disclosed
US-9496439-B2 Polyester film, back sheet for solar cell, and solar cell module FUJIFILM CORPORATION (JP) 2016-11-15 US disclosed
US-8987440-B2 Cyclic carbodiimide compounds TEIJIN LIMITED (JP) 2015-03-24 US disclosed
US-8816018-B2 Resin composition comprising a cyclic carbodiimide TEIJIN LIMITED (JP) 2014-08-26 US disclosed
US-20140158195-A1 BIAXIALLY STRETCHED POLYESTER FILM, METHOD OF PRODUCING SAME, AND SOLAR CELL MODULE FUJIFILM CORPORATION (JP) 2014-06-12 US disclosed
US-20140130867-A1 POLYESTER FILM, METHOD FOR PRODUCING THE SAME, BACK SHEET FOR SOLAR CELL, AND SOLAR CELL MODULE FUJIFILM CORPORATION (JP) 2014-05-15 US disclosed
US-20130079510-A1 CYCLIC CARBODIIMIDE COMPOUND TEIJIN LIMITED (JP) 2013-03-28 US disclosed
US-20130005875-A1 RESIN COMPOSITION COMPRISING A CYCLIC CARBODIIMIDE TEIJIN LIMITED (JP) 2013-01-03 US disclosed
US-20120302676-A1 FILM TEIJIN LIMITED (JP) 2012-11-29 US disclosed
US-20120289625-A1 POLYLACTIC ACID COMPOSITION TEIJIN LIMITED (JP) 2012-11-15 US disclosed
US-20120184166-A1 FIBER AND FIBER STRUCTURE TEIJIN LIMITED (JP) 2012-07-19 US disclosed
US-20110251384-A1 CYCLIC CARBODIIMIDE COMPOUNDS TEIJIN LIMITED (JP) 2011-10-13 US disclosed
US-20110237755-A1 METHOD OF USING A CYCLIC CARBODIIMIDE TEIJIN LIMITED (JP) 2011-09-29 US disclosed
US-20110224385-A1 RESIN COMPOSITION COMPRISING A CYCLIC CARBODIIMIDE TEIJIN LIMITED (JP) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110251384-A1 CYCLIC CARBODIIMIDE COMPOUNDS APEX1, LIG4, EPB41 ABCG2 4654/4885PKM 3770/4885TSHR 4557/4885
US-20130079510-A1 CYCLIC CARBODIIMIDE COMPOUND CNOT9, CNOT1, ARPC4 ABCG2 4288/4885PKM 4516/4885TSHR 2964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.