Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.48 |
| ▸ | VHL | P40337 | 1/20 | 0.47 |
| ▸ | ELOC | Q15369 | 1/20 | 0.47 |
| ▸ | ELOB | Q15370 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853329 | 0.80 | GSK3B (0.68) | LMNAMAPTMEN1KMT2AHSD17B3 | |
| SCHEMBL9442261 | 0.74 | NOTUM (0.59) | KMT2AHSD17B3NOTUM | |
| SCHEMBL3526981 | 0.72 | NOTUM (0.61) | MAPTMEN1KMT2AHSD17B3NOTUM | |
| SCHEMBL29875631 | 0.72 | NOTUM (0.61) | MAPTMEN1KMT2AHSD17B3NOTUM | |
| SCHEMBL9629768 | 0.71 | GSK3B (0.57) | MEN1KMT2AHSD17B3GSK3BNOTUM | |
| SCHEMBL9843864 | 0.71 | NOTUM (0.56) | HSD17B3NOTUMNCOR2 | |
| SCHEMBL8870414 | 0.70 | NOX1 (0.73) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9045039 | 0.69 | NOTUM (0.61) | MAPTMEN1KMT2AHSD17B3NOTUM | |
| SCHEMBL9778382 | 0.69 | NOX1 (0.54) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8853311 | 0.68 | GSK3B (0.68) | LMNAMAPTMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292824-B1 | PROCESS FOR THE NUCLEAR CHLORINATION OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4851596-A | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |