Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 10/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.40 |
| ▸ | HK1 | P19367 | 2/20 | 0.38 |
| ▸ | HK2 | P52789 | 2/20 | 0.38 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324213 | 0.94 | TLR4 (0.48) | TLR4SELPHK1HK2SYNJ2 | |
| SCHEMBL9324219 | 0.94 | TLR4 (0.48) | TLR4SELPHK1HK2SYNJ2 | |
| SCHEMBL10775868 | 0.94 | TLR4 (0.48) | TLR4SELPHK1HK2SYNJ2 | |
| SCHEMBL10775862 | 0.94 | TLR4 (0.48) | TLR4SELPHK1HK2SYNJ2 | |
| SCHEMBL10354481 | 0.93 | TLR4 (0.52) | TLR4SELP | |
| SCHEMBL9624581 | 0.90 | TLR4 (0.51) | TLR4SELP | |
| SCHEMBL9624577 | 0.90 | TLR4 (0.51) | TLR4SELP | |
| SCHEMBL10354024 | 0.87 | TLR4 (0.38) | TLR4SELP | |
| SCHEMBL9521826 | 0.85 | MAPK1 (0.51) | TLR4SELPSYNJ2 | |
| SCHEMBL9521833 | 0.85 | MAPK1 (0.51) | TLR4SELPSYNJ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180608-B1 | 2,3-DIAMINO-2,3-DIDESOXYHEXOSE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | SANDOZ AG (CH) | 1990-07-25 | — | — | EP | disclosed |
| US-4698331-A | 2,3-diamino-2,3-didesoxyhexose derivatives and their use | SANDOZ LTD. (CH) | 1987-10-06 | — | — | US | disclosed |
| EP-0180608-A1 | 2,3-DIAMINO-2,3-DIDESOXYHEXOSE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE. | SANDOZ AG (CH) | 1986-05-14 | — | — | EP | disclosed |
| WO-1985004881-A1 | 2,3-DINAMO-2,3-DIDESOXYHEXOSE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | SANDOZ AG (CH) | 1985-11-07 | — | — | WO | disclosed |