Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 8/20 | 0.48 |
| ▸ | HK1 | P19367 | 2/20 | 0.45 |
| ▸ | HK2 | P52789 | 2/20 | 0.45 |
| ▸ | HRAS | P01112 | 1/20 | 0.41 |
| ▸ | SYNJ2 | O15056 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324219 | 1.00 | TLR4 (0.48) | TLR4HK1HK2HRASSYNJ2 | |
| SCHEMBL9324213 | 1.00 | TLR4 (0.48) | TLR4HK1HK2HRASSYNJ2 | |
| SCHEMBL10775868 | 1.00 | TLR4 (0.48) | TLR4HK1HK2HRASSYNJ2 | |
| SCHEMBL10354142 | 0.94 | TLR4 (0.43) | TLR4HK1HK2SYNJ2KDM4E | |
| SCHEMBL9624577 | 0.90 | TLR4 (0.51) | TLR4SELPMAPK1 | |
| SCHEMBL9624581 | 0.90 | TLR4 (0.51) | TLR4SELPMAPK1 | |
| SCHEMBL10354481 | 0.88 | TLR4 (0.52) | TLR4SELP | |
| SCHEMBL9521826 | 0.88 | MAPK1 (0.51) | TLR4SYNJ2SELPMAPK1 | |
| SCHEMBL9521833 | 0.88 | MAPK1 (0.51) | TLR4SYNJ2SELPMAPK1 | |
| SCHEMBL9472566 | 0.87 | TLR4 (0.43) | TLR4HK1HK2SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1987000174-A2 | 1-O-PHOSPHONO-SACCHARIDES, METHOD FOR THE PRODUCTION AND UTILIZATION THEREOF | SANDOZ-ERFINDUNGEN VERWALTUNGSGESELLSCHAFT M.B.H. (AT) | 1987-01-15 | — | — | WO | disclosed |