Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681756 | 0.92 | F10 (0.44) | F10MCHR1HTR2CCSNK1DCSNK1E | |
| SCHEMBL1034169 | 0.90 | HIF1A (0.51) | F10HIF1AEPAS1 | |
| SCHEMBL1031737 | 0.87 | HIF1A (0.51) | MCHR1HTR2CHIF1AEPAS1 | |
| SCHEMBL1083522 | 0.83 | F10 (0.45) | F10MCHR1HTR2CHIF1AEPAS1 | |
| SCHEMBL2681885 | 0.83 | F10 (0.44) | F10HIF1AEPAS1 | |
| SCHEMBL1029775 | 0.82 | HIF1A (0.46) | F10HIF1AEPAS1ACHEGSK3B | |
| Hydrochloric Acid SCHEMBL2681741 | 0.82 | F10 (0.43) | F10HIF1AEPAS1 | |
| SCHEMBL1847421 | 0.82 | ACKR3 (0.49) | F10MCHR1HTR2CHIF1AEPAS1 | |
| SCHEMBL4401608 | 0.82 | F10 (0.44) | F10MCHR1HTR2CGSK3BACKR3 | |
| SCHEMBL2680721 | 0.81 | HIF1A (0.42) | F10MCHR1HTR2CHIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003684-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-01-13 | — | — | WO | disclosed |