Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2682590 | 0.92 | F10 (0.42) | F10MCHR1HTR2CEGLN1HDAC1 | |
| SCHEMBL4405599 | 0.85 | MCHR1 (0.44) | F10MCHR1HTR2CHDAC1 | |
| SCHEMBL1035444 | 0.83 | F10 (0.47) | F10MCHR1HTR2CHIF1AEPAS1 | |
| SCHEMBL1034169 | 0.82 | HIF1A (0.51) | F10HIF1AEPAS1 | |
| SCHEMBL1726317 | 0.81 | MCHR1 (0.48) | MCHR1HTR2CHDAC1KCNH2 | |
| SCHEMBL2680635 | 0.79 | F10 (0.43) | F10MCHR1HTR2CHDAC1ACKR3 | |
| SCHEMBL1029775 | 0.79 | HIF1A (0.46) | F10HIF1AEPAS1 | |
| SCHEMBL2680949 | 0.78 | F10 (0.42) | F10MCHR1HTR2CHDAC1HIF1A | |
| SCHEMBL2681297 | 0.76 | F10 (0.40) | F10MCHR1HTR2CHDAC1 | |
| SCHEMBL4401608 | 0.75 | F10 (0.44) | F10MCHR1HTR2CHDAC1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011003684-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-01-13 | — | — | WO | disclosed |