SCHEMBL10354566

FC1(F)C(F)(F)C(F)(F)C(F)(C(F)(F)C23C(F)(F)C(F)(F)C(F)(F)C(F)(F)C2(F)C(F)(F)C(F)(F)C(F)(F)C3(F)F)C(F)(F)C1(F)F

nearest known ligand 0.37

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	1/20	0.37

▸	KMT2A	Q03164	1/20	0.37

▸	TDP1	Q9NUW8	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15755501	0.77	MEN1 (0.50)	MEN1KMT2ATDP1
SCHEMBL3749601	0.76	MEN1 (0.35)	MEN1KMT2ATDP1
SCHEMBL11093290	0.75	MEN1 (0.33)	MEN1KMT2ATDP1
SCHEMBL1332718	0.74	MEN1 (0.47)	MEN1KMT2ATDP1
SCHEMBL11612420	0.73	MEN1 (0.44)	MEN1KMT2ATDP1
SCHEMBL8402370	0.73	MEN1 (0.44)	MEN1KMT2ATDP1
SCHEMBL11615307	0.69	MEN1 (0.39)	MEN1KMT2ATDP1
SCHEMBL1279924	0.69	MEN1 (0.33)	MEN1KMT2ATDP1
SCHEMBL10428054	0.65	MEN1 (0.35)	MEN1KMT2ATDP1
SCHEMBL25327648	0.65	MEN1 (0.50)	MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0253529-B1	FLUORINATED POLYCYCLIC COMPOUNDS	ISC CHEMICALS LIMITED (GB)	1990-09-26	—	—	EP	claimed
EP-0253529-A1	Fluorinated polycyclic compounds	ISC CHEMICALS LIMITED (GB)	1988-01-20	—	—	EP	claimed
EP-0253529-B1	FLUORINATED POLYCYCLIC COMPOUNDS	ISC CHEMICALS LIMITED (GB)	1990-09-26	—	—	EP	disclosed
EP-0253529-A1	Fluorinated polycyclic compounds	ISC CHEMICALS LIMITED (GB)	1988-01-20	—	—	EP	disclosed