SCHEMBL11093290

SCHEMBL11093290

FC1(F)C(F)(F)C(F)(F)C(F)(C(F)(F)C2(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C2(F)F)C(F)(F)C1(F)F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15755501 0.87 MEN1 (0.50) MEN1KMT2ATDP1
SCHEMBL1332718 0.84 MEN1 (0.47) MEN1KMT2ATDP1
SCHEMBL37587 0.75 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL196722 0.75 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL15186 0.75 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL10354579 0.75 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL554739 0.75 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL10354566 0.75 MEN1 (0.37) MEN1KMT2ATDP1
SCHEMBL33642 0.72 MEN1 (0.31) MEN1KMT2ATDP1
SCHEMBL12506200 0.72 MEN1 (0.31) MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4453028-A BLOOD SUBSTITUTES BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, THE 1984-06-05 US disclosed