SCHEMBL10354569

SCHEMBL10354569

CC(C)[C@H](NC(=O)COc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SDCBP O00560 2/20 0.59
SDC2 P34741 2/20 0.59
MBTPS1 Q14703 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
ALDH1A1 P00352 3/20 0.55
KDM4E B2RXH2 1/20 0.55
NPSR1 Q6W5P4 2/20 0.53
TSHR P16473 1/20 0.53
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
GAA P10253 1/20 0.51
HPGD P15428 1/20 0.51
HSD17B10 Q99714 1/20 0.51
ATF4 P18848 3/20 0.50
GPR34 Q9UPC5 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10605111 0.90 ALDH1A1 (0.53) SDCBPSDC2SMN1; SMN2ALDH1A1KDM4E
SCHEMBL10605108 0.90 ALDH1A1 (0.53) SDCBPSDC2SMN1; SMN2ALDH1A1KDM4E
SCHEMBL10872087 0.88 ALDH1A1 (0.51) SDCBPSDC2SMN1; SMN2ALDH1A1KDM4E
SCHEMBL10872082 0.88 ALDH1A1 (0.51) SDCBPSDC2SMN1; SMN2ALDH1A1KDM4E
SCHEMBL10354459 0.87 ALDH1A1 (0.53) SMN1; SMN2ALDH1A1KDM4ENPSR1MEN1
SCHEMBL11324889 0.87 MBTPS1 (0.67) MBTPS1SMN1; SMN2ALDH1A1KDM4ENPSR1
SCHEMBL5711200 0.87 MBTPS1 (0.67) MBTPS1SMN1; SMN2ALDH1A1KDM4ENPSR1
SCHEMBL10873062 0.85 ALDH1A1 (0.74) SMN1; SMN2ALDH1A1KDM4ENPSR1MEN1
SCHEMBL8248742 0.83 SMN1; SMN2 (0.64) SMN1; SMN2ALDH1A1KDM4ENPSR1TSHR
SCHEMBL10354478 0.83 NPSR1 (0.52) SMN1; SMN2ALDH1A1KDM4ENPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0205327-B1 PHENOXYACETYLAMIDE DERIVATIVE AND PROCESS FOR PRODUCTION AND USE THEREOF SUNTORY LIMITED (JP) 1990-09-26 EP disclosed
EP-0206605-B1 N-ACYL AMINO ACID DERIVATIVE AND PROCESS FOR PRODUCTION AND USE THEREOF SUNTORY LIMITED (JP) 1989-10-25 EP disclosed
US-4778514-A HERBICIDES SUNTORY LIMITED (JP) 1988-10-18 US disclosed
EP-0205327-A1 Phenoxyacetylamide derivative and process for production and use thereof SUNTORY LIMITED (JP) 1986-12-17 EP disclosed