SCHEMBL10354570

SCHEMBL10354570

CC(C)(CC(O)CCl)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.44
ACACA Q13085 1/20 0.44
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 1/20 0.33
ACLY P53396 1/20 0.32
TSHR P16473 3/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
AR P10275 1/20 0.31
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7698392 0.81 ACACB (0.47) ACACBACACAACLYTSHRALDH1A1
SCHEMBL28964266 0.79 ACACB (0.45) ACACBACACACA2ACLYTSHR
SCHEMBL28322374 0.76 ACACB (0.47) ACACBACACAACLYTSHRALDH1A1
SCHEMBL19283475 0.76 ACACB (0.42) ACACBACACAACLYTSHRALDH1A1
SCHEMBL6905024 0.72 ACACB (0.53) ACACBACACAACLY
SCHEMBL28552427 0.72 ACACB (0.41) ACACBACACAACLYTSHRALDH1A1
SCHEMBL11913364 0.72
SCHEMBL1131865 0.71 ACACB (0.38) ACACBACACAACLYTSHRALDH1A1
SCHEMBL27677760 0.71 ACACB (0.56) ACACBACACAACLY
SCHEMBL301722 0.70 ACACB (0.40) ACACBACACAACLYTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0390777-A1 CYCLOCARBONATE COMPOUNDS DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-10-10 EP disclosed
WO-1989000565-A1 CYCLOCARBONATE COMPOUNDS DAINIPPON INK & CHEMICALS, INC. (JP) 1989-01-26 WO disclosed