Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28552427 | 0.81 | ACACB (0.41) | ACACBACACATSHRALDH1A1ACLY | |
| SCHEMBL29262309 | 0.80 | — | — | |
| SCHEMBL301722 | 0.79 | ACACB (0.40) | ACACBACACATSHRALDH1A1ACLY | |
| SCHEMBL28065497 | 0.77 | ACACB (0.39) | ACACBACACATSHRALDH1A1ACLY | |
| SCHEMBL28065512 | 0.77 | ACACB (0.39) | ACACBACACATSHRALDH1A1ACLY | |
| SCHEMBL17299152 | 0.75 | FDPS (0.41) | ACACBACACATSHRALDH1A1ACLY | |
| SCHEMBL7698226 | 0.75 | ACACB (0.42) | ACACBACACATSHRALDH1A1ACLY | |
| SCHEMBL9710109 | 0.75 | ACACB (0.38) | ACACBACACATSHRALDH1A1ACLY | |
| SCHEMBL9688268 | 0.75 | ACACB (0.38) | ACACBACACATSHRALDH1A1ACLY | |
| SCHEMBL11129258 | 0.75 | ACACB (0.38) | ACACBACACATSHRALDH1A1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087680-B1 | CRYSTALLINE DIASTEREOMERIC L-ALPHA-METHYLDOPA POE ESTER | MERCK & CO. INC. (US) | 1985-11-21 | — | — | EP | claimed |
| US-4440942-A | Crystalline diastereomeric L-alpha-methyldopa POE ester and process for its preparation | MERCK & CO., INC. (US) | 1984-04-03 | — | — | US | claimed |
| EP-0087680-A1 | Crystalline diastereomeric L-alpha-methyldopa POE ester | MERCK & CO. INC. (US) | 1983-09-07 | — | — | EP | claimed |
| EP-1812381-B1 | ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND AND PROCESS FOR PRODUCING THE SAME, AND REACTIVE MONOMER, REACTIVE (METH)ACRYLATE POLYMER AND ITS USE | SHOWA DENKO KK (JP) | 2011-02-16 | — | — | EP | disclosed |
| US-7579066-B2 | Ethylenically unsaturated group-containing isocyanate compound and process for producing the same, and reactive monomer, reactive (meth) acrylate polymer and its use | SHOWA DENKO K.K. (JP) | 2009-08-25 | — | — | US | disclosed |
| US-20080132597-A1 | Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use | RESONAC CORPORATION (JP) | 2008-06-05 | — | — | US | disclosed |
| US-5354549-A | Iodinated esters | NYCOMED IMAGING AS (NO) | 1994-10-11 | — | — | US | disclosed |
| EP-0300828-B1 | IODINATED ESTERS | NYCOMED AS (NO) | 1992-03-18 | — | — | EP | disclosed |
| US-4914222-A | DISSOLVING ESTER IN NONPOLAR WATER-IMMISCIBLE SOLVENT, ADDING HYDROXYLATED SOLVENT AND OXYGENATED ACID, CRYSTALLIZING SALT | MERCK & CO., INC. (US) | 1990-04-03 | — | — | US | disclosed |
| WO-1989000988-A1 | IODINATED ESTERS | NYCOMED AS (NO) | 1989-02-09 | — | — | WO | disclosed |
| EP-0300828-A1 | Iodinated esters | NYCOMED AS (NO) | 1989-01-25 | — | — | EP | disclosed |
| EP-0030734-A1 | Tyrosine derivatives, a process for preparing the same and a pharmaceutical composition containing the same for treating hypertension | MERCK & CO. INC. (US) | 1981-06-24 | — | — | EP | disclosed |
| US-4254273-A | INTERMEDIATES FOR HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1981-03-03 | — | — | US | disclosed |
| US-4198413-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4143146-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4058530-A | PHENYLALANINE, ANTIHYPERTENSIVE | MERCK & CO., INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4051169-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1977-09-27 | — | — | US | disclosed |
| US-4038411-A | ANTIHYPERTENSIVE AMINO ACID ESTERS | MERCK & CO., INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-3988341-A | Esterification process | MERCK & CO., INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3983138-A | HYPOTENSIVES | MERCK & CO., INC. (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132597-A1 | Ethylenically Unsaturated Group-Containing Isocyanate Compound and Process for Producing the Same, and Reactive Monomer, Reactive (Meth) Acrylate Polymer and its Use | ACAD9, ELOVL6, ELOVL5 | ACACB 209/4885ACACA 168/4885TSHR 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.