Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.62 |
| ▸ | PGR | P06401 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.62 |
| ▸ | AR | P10275 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478951 | 1.00 | NR3C1 (0.62) | NR3C1PGRLMNAHIF1AAR | |
| SCHEMBL7741859 | 1.00 | NR3C1 (0.62) | NR3C1PGRLMNAHIF1AAR | |
| SCHEMBL7740470 | 0.94 | NR3C1 (0.64) | NR3C1PGRLMNAHIF1AAR | |
| SCHEMBL8077837 | 0.94 | NR3C1 (0.64) | NR3C1PGRLMNAHIF1AAR | |
| SCHEMBL26228034 | 0.91 | NR3C1 (0.65) | NR3C1PGRLMNAHIF1AAR | |
| SCHEMBL8135815 | 0.91 | NR3C1 (0.63) | NR3C1PGRLMNAHIF1AAR | |
| SCHEMBL5033116 | 0.91 | NR3C1 (0.73) | NR3C1PGRLMNAHIF1AAR | |
| SCHEMBL10073752 | 0.91 | NR3C1 (0.73) | NR3C1PGRLMNAHIF1AAR | |
| SCHEMBL21153780 | 0.91 | NR3C1 (0.73) | NR3C1PGRLMNAHIF1AAR | |
| SCHEMBL21153648 | 0.91 | NR3C1 (0.73) | NR3C1PGRLMNAHIF1AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232690-B1 | NOVEL 16,17-ACETALSUBSTITUTED PREGNANE-21-OIC ACID DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL PREPARATION CONTAINING THEM | Aktiebolaget Draco (SE) | 1990-10-31 | — | — | EP | disclosed |