Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 5/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355306 | 1.00 | RAB9A (0.52) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10355334 | 0.99 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10355333 | 0.99 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10340357 | 0.95 | MAPT (0.59) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10354702 | 0.95 | MAPT (0.59) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10340358 | 0.95 | MAPT (0.59) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10580891 | 0.95 | MAPT (0.59) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10355025 | 0.95 | MAPT (0.59) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9817465 | 0.95 | MAPT (0.59) | RAB9AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10354690 | 0.95 | MAPT (0.59) | RAB9AMAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152808-B1 | NITROGEN CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1990-09-12 | — | — | EP | disclosed |
| US-4882082-A | PYRIMIDINE DERIVATIVE LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-11-21 | — | — | US | disclosed |
| US-4752414-A | LIQUID CRYSTAL PHASES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-06-21 | — | — | US | disclosed |